
Cardiovascular Imaging Laboratory
|
 |
|
Pablo Soto, M.D.
Instructor in Medicine, Cardiovascular Division
|
|
|
Dept of Radiology
Washington University
Campus Box 8225
510 S. Kinshighway Blvd
St. Louis, MO 63130
|
|

Mentor: Robert J. Gropler, MD - "Impact of Aging on Myocardial Metabolic Remodeling: Role of Nitric Oxide"
Curriculum Vitae
CURRENT POSITION
Instructor in Medicine, Cardiovascular Division
Washington University School of Medicine, St. Louis, Missouri
EDUCATION AND TRAINING
|
2004-present
|
Instructor in Medicine, Cardiovascular Division, Wash U.
School of Medicine
|
|
2001-2004
|
Research Fellow, Cardiovascular Division, Washington U. School
of Medicine
|
|
1999-2001
|
Barnes-Jewish Hospital, Clinical Fellow in Cardiology
|
|
1996-1999
|
University of Michigan Medical Center, Resident in Internal Medicine
|
|
1991-1994
|
Columbia-Presbyterian Medical Center, Resident in General Surgery
|
|
1987-1991
|
Duke University School of Medicine, MD 1991
|
|
1983-1987
|
Princeton University, BSE 1987, Aerospace Engineering, Cum Laude Graduate
|
PRIOR RESEARCH EXPERIENCE
|
1994-1996
|
Cardiovascular Research Fellow
Department of Surgery, Columbia University, New York, NY
Mentor: Henry M. Spotnitz, MD
Project: Role of Ventricular Compliance in Acute Allograft Rejection
|
|
1989-1990
|
Medical Student
Department of Surgery, Duke University School of Medicine
Mentor: J. Scott Rankin, MD
Project: Arterial Windkessel Modeling
|
|
1986-1987
|
Undergraduate
Department of Mechanical and Aerospace Engineering, Princeton University
Mentor: Richard B. Miles, PhD
Project: 3-D MRI Reconstruction
|
|
1985
|
Summer Undergraduate Research Fellow
Department of Biochemistry, University of Alabama at Birmingham
Mentor: Kenneth B. Taylor, PhD
Project: Optimal Harvesting Techniques for Bacterial Cultures
|
RESEARCH SUPPORT - CURRENT AND PRIOR
|
Granting Agency:
|
National Institutes of Health, Mentored Patient-Oriented
Research Career Development Award 1 K23 HL077179-01
|
|
Role:
|
Principal Investigator
|
|
Title:
|
"Role of Estrogen/SERMs on Cardiac Fatty Acid Metabolism"
|
|
Duration:
|
9/30/2004 to 8/31/2009
|
|
Granting Agency:
|
American Heart Association, Heartland Affiliate Postdoctoral Fellowship 0225573Z
|
|
Role:
|
Principal Investigator
|
|
Title:
|
"Impact of Aging on Myocardial Metabolic Remodeling: Role of Nitric Oxide"
|
|
Duration:
|
7/1/2002 to 6/30/2004
|
|
Granting Agency:
|
National Institutes of Health, National Research Service Award Postdoctoral Fellowship 1 F32 HL09356-01
|
|
Role:
|
Principal Investigator
|
|
Title:
|
"Left Ventricular Compliance in Acute Allograft Rejection"
|
|
Duration:
|
7/1/1995 to 6/30/1996
|
|
Total Cost:
|
$31,200
|
PRESENTATIONS AT NATIONAL MEETINGS
- Improved Aerobic Capacity with Exercise Training in the Elderly
Correlates with Increased Myocardial Fatty Acid Uptake During Dobutamine.
50th Annual Meeting of the Society of Nuclear Medicine, New Orleans, LA;
June 24, 2003.
- Impact of Estrogen on Myocardial Fatty Acid Utilization and Oxidation
in Postmenopausal Women -
AstraZeneca Cardiovascular Young Investigator's Forum, San Francisco, CA;
Oct 11, 2002.
- Effect of Inducible Nitric Oxide Synthase Inhibition on Diastolic
Properties of the Rejecting Rat Heart -
72nd Scientific Session,
American Heart Association, New Orleans, LA, Nov 16, 1996.
- Timing of Pre-Transplantation Cyclosporine Affects Left Ventricular
Function in the Rat -
Experimental Biology, Washington, DC, May 12, 1996.
- Diastolic Properties During Rejection of the Heterotopically Transplanted
Rat Heart -
81st Annual Clinical Congress, American College of Surgeons, New
Orleans, October 11, 1995.
HONORS
|
2004
|
Burton E. Sobel Award for Excellence in Cardiovascular Research -
Washington Univ.
|
|
2002
|
Finalist, AstraZeneca Cardiovascular Young Investigator's Forum
|
|
1987
|
Cum Laude Graduate, Princeton University
|
|
1987
|
The Donald Janssen Dike Award for Excellence in Undergraduate Research - 2nd Prize.
|
|
1985
|
Tau Beta Pi Engineering Honor Society - Treasurer
|
LICENSES AND BOARD CERTIFICATIONS
|
2000-present
|
Missouri Medical License #2000175095
|
|
1998-present
|
Michigan Medical License #4301068054
|
|
1994-1998
|
New York Medical License #194669
|
|
2000
|
Diplomate, American Board of Internal Medicine
|
|
2002
|
Diplomate, Cardiovascular Diseases
|
|
2003
|
Testamur, Adult Echocardiography, National Board of Echocardiography
|
|
2003
|
Certification Board of Nuclear Cardiology
|
Publications - Manuscripts
- Herrero P, Soto PF, Ware Z, Delano DA, Gropler RJ. Impact of
hormone replacement on myocardial fatty acid metabolism: potential role
of estrogen. (In Review)
- Gropler RJ and Soto PF. Recent advances in cardiac positron
emission tomography in the clinical management of the cardiac patient.
Curr Cardiol Rep 2004;6(1):20-6.
- Soto PF, Herrero P, Kates AM, Dence C, Ehsani AA, Davila-Roman V,
Schectmann KB, Gropler RJ. Impact of aging on myocardial metabolic
response to dobutamine. Amer J Physiol: Heart and Circulatory
Physiology 2003;285:H2158-2164.
- Kates AM, Herrero P, Dence C, Soto PF, Srinivasan M, Delano D,
Ehsani A, Gropler RJ. Impact of Aging on Substrate Metabolism by the Human
Heart. J Amer Coll Cardiol2003;41(2):293-299.
- Soto PF, Kovacs SJ. The Diagnosis and Treatment of Diastolic Heart
Failure. Cardiovascular Reviews and Reports 2002;23(9):493-500.
- Soto PF, Jia CX, Rabkin DA, Carter YM, Sardo MJ, Hsu DT, Fisher DT,
Pinsky D, Spotnitz HM. Improvement of rejection-induced diastolic
abnormalities in rat cardiac allografts with inducible nitric oxide synthase
inhibition. J Thorac Cardiovasc Surg 2000;120:39-46.
- Starr JP, Jia CX, Rabkin DA, Amirhamzeh MM, Hart JP, Hsu DT, Soto P,
Pinsky D, Spotnitz HM. Pressure volume curves in arrested heterotopic rat
heart isografts: role of improved myocardial protection. J Surgical
Res 1999;86(1):123-9.
- Soto PF, Jia CX, Carter YM, Rabkin D, Starr JP. Amirhamzeh MM, Hsu
DT, Sciacca R, Fisher PE, Spotnitz HM. Effect of improved myocardial
protection on edema and diastolic properties of the rat left ventricle during
acute allograft rejection. J Heart Lung Transplant 1998;17(6):608-16.
- Cabreriza SE, Dean DA, Amirhamzeh MM, Jia CX, Sciacca R, Soto P,
Spotnitz HM. A method for detecting changes in left ventricular mass during
variations in filling volume. J Am Soc Echocardiogr 1998;11(4):356-64.
- Carter YM, Jia CX, Soto PF, Starr JP, Rabkin DG, Hsu DT, Fisher PE,
Spotnitz HM. Diastolic properties, myocardial water content, and histologic
condition of the rat left ventricle: effect of varied osmolarity of a coronary
perfusate. J Heart Lung Transplant 1998;17(2):140-9.
- Dean DA, Jia CX, Cabreriza SE, Soto PF, Rabkin DG, Sardo MJ, Chalik
N, Spotnitz HM. Retrograde coronary perfusion: effects on iatrogenic edema and
diastolic properties. Ann Thorac Surg 1998;65(2):449-5.
- Soto PF, Jia CX, Carter YC, Starr JP, Amirhamzeh MMR, Spotnitz HM.
Diastolic properties during rejection of the heterotopically transplanted rat
heart. Surg Forum 1995;46:452-55.
- Shim Y, Pasipoularides A, Straley CA, Hampton TG, Soto PF, Owen CH,
Davis JW, Glower DD. Arterial windkessel parameter estimation: a new
time-domain method. Ann Biomed Engineering 1994;22(1):66-7.
Publications - Abstracts
- Soto PF, Herrero P, Baumstark JM, DeLano DA, Ehsani AA,
Gropler RJ. Improved Aerobic Capacity with Exercise Training in the
Elderly Correlates with Increased Myocardial Fatty Acid Uptake During
Dobutamine. J Nuc Med (suppl.) 2003;44(5):106P.
- Soto PF, Singh J, Lisauskas J, Meyer TE, Ehsani AA, Kovacs SJ.
The relation of aerobic exercise capacity (peak VO2) to Doppler E-wave
derived indexes of diastolic function in patients with advanced heart failure.
Circulation (suppl.) 2001;104(17):II-411.
- Soto PF, Jia CX, Sardo MJ, Fisher PE, Spotnitz HM. Effect of
nitric oxide synthase inhibition on diastolic properties of the rejecting rat
heart. Circulation (suppl.) 1996;94(8):I-590.
 |
 |
|